abstract：BACKGROUND:Crystalline/chrysalis structures (CS) are white shiny streaks that can only be seen with polarized dermatoscopy. OBJECTIVES:We sought to estimate the prevalence and assess the clinical significance of CS in melanocytic and nonmelanocytic lesions. METHODS:This was a prospective observational study in which ...

journal_title：Journal of the American Academy of Dermatology

authors： Balagula Y,Braun RP,Rabinovitz HS,Dusza SW,Scope A,Liebman TN,Mordente I,Siamas K,Marghoob AA

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The potential for wrong-site surgery is a growing concern in dermatology. OBJECTIVE:The purpose of this study was to determine the incidence of difficulty with surgical site identification and possible confounding factors. METHODS:This was a prospective study on 333 Mohs cases performed between April 1, 20...

journal_title：Journal of the American Academy of Dermatology

authors： Rossy KM,Lawrence N

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Connective tissue nevi (CTN) may be isolated, either sporadic or hereditary, or syndromic as in the Buschke-Ollendorff syndrome. Few publications have addressed the variable clinical and histopathologic expression of these benign hamartomas. OBJECTIVE:We sought to characterize the clinical and histopatholog...

journal_title：Journal of the American Academy of Dermatology

authors： Saussine A,Marrou K,Delanoé P,Bodak N,Hamel D,Picard A,Sassolas B,de Prost Y,Lemerrer M,Fraitag S,Bodemer C

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:A task force of the National Psoriasis Foundation Medical Board was convened to evaluate treatment options for pustular psoriasis. Meetings were held by teleconference. Consensus on treatment of pustular psoriasis was achieved. Pustular psoriasis has been classified into localized and generalized forms. Ther...

journal_title：Journal of the American Academy of Dermatology

authors： Robinson A,Van Voorhees AS,Hsu S,Korman NJ,Lebwohl MG,Bebo BF Jr,Kalb RE

更新日期：2012-08-01 00:00:00

abstract：:Chemotherapy-induced alopecia is a distressing side effect common to certain treatment regimens in oncology. Unfortunately, chemotherapy-induced alopecia is an often overlooked or minor factor among our current research priorities and thus advances in amelioration have been minimal. This review offers a comprehensive ...

journal_title：Journal of the American Academy of Dermatology

authors： Chon SY,Champion RW,Geddes ER,Rashid RM

更新日期：2012-07-01 00:00:00

abstract：:Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised individuals who have higher risk of malignant transformation and are more difficult to treat. This is part I of a two-p...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Kovarik CL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Studies of noncutaneous and cutaneous malignancies support the hypothesis that poor risk-perception status contributes to health disparity. OBJECTIVE:We evaluated skin cancer (SC) risk perceptions across race and other demographic markers using the Health Information National Trends Survey (HINTS) and compa...

journal_title：Journal of the American Academy of Dermatology

authors： Buster KJ,You Z,Fouad M,Elmets C

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Curcuminoids are components of turmeric (Curcuma longa) that possess anti-inflammatory properties. OBJECTIVE:We sought to study the efficacy of curcuminoids in controlling the signs and symptoms of oral lichen planus, at doses of 6000 mg/d (3 divided doses), and their safety at this dose. METHODS:Twenty co...

journal_title：Journal of the American Academy of Dermatology

authors： Chainani-Wu N,Madden E,Lozada-Nur F,Silverman S Jr

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) and imiquimod are the treatments of choice for actinic keratosis (AK). As they have different mechanisms of action, it seems reasonable to assume that applying both treatments sequentially would be efficacious. OBJECTIVES:We sought to determine which of these therapeutic modalitie...

journal_title：Journal of the American Academy of Dermatology

authors： Serra-Guillén C,Nagore E,Hueso L,Traves V,Messeguer F,Sanmartín O,Llombart B,Requena C,Botella-Estrada R,Guillén C

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Pulsed dye laser (PDL) is the gold standard for treatment of port-wine stain (PWS) birthmarks but multiple treatments are required and complete resolution is often not achieved. Posttreatment vessel recurrence is thought to be a factor that limits efficacy of PDL treatment of PWS. Imiquimod 5% cream is an im...

journal_title：Journal of the American Academy of Dermatology

authors： Tremaine AM,Armstrong J,Huang YC,Elkeeb L,Ortiz A,Harris R,Choi B,Kelly KM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Topical antibiotics are not indicated for routine postoperative care in clean dermatologic procedures, but may be widely used. OBJECTIVE:We sought to describe topical antibiotic use in clean dermatologic surgical procedures in the United States. METHODS:The 1993 to 2007 National Ambulatory Medical Care Sur...

journal_title：Journal of the American Academy of Dermatology

authors： Levender MM,Davis SA,Kwatra SG,Williford PM,Feldman SR

更新日期：2012-03-01 00:00:00

abstract：:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sha...

journal_title：Journal of the American Academy of Dermatology

authors： Murrell DF,Daniel BS,Joly P,Borradori L,Amagai M,Hashimoto T,Caux F,Marinovic B,Sinha AA,Hertl M,Bernard P,Sirois D,Cianchini G,Fairley JA,Jonkman MF,Pandya AG,Rubenstein D,Zillikens D,Payne AS,Woodley D,Zambruno

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Despite increasing therapies for moderate to severe psoriasis, dermatologists' treatment preferences are unknown. OBJECTIVE:We sought to assess dermatologists' preferences for first-line treatments and their selection determinants. METHODS:We surveyed 1000 US dermatologists (500 National Psoriasis Foundati...

journal_title：Journal of the American Academy of Dermatology

authors： Wan J,Abuabara K,Troxel AB,Shin DB,Van Voorhees AS,Bebo BF Jr,Krueger GG,Callis Duffin K,Gelfand JM

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Psoriasis significantly impairs work productivity and daily activities. OBJECTIVES:We sought to examine the effects of adalimumab on psoriasis-related work productivity and activity impairment and associations between the impairment and psoriasis severity in patients with moderate to severe psoriasis. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Kimball AB,Yu AP,Signorovitch J,Xie J,Tsaneva M,Gupta SR,Bao Y,Mulani PM

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Unwanted tattoos are treated with Q-switched lasers. Despite a series of treatments, efficacy is limited. OBJECTIVE:We compared a single Q-switched laser treatment pass with 4 treatment passes separated by 20 minutes. METHODS:Eighteen tattoos on 12 adults were divided in half and randomized. One half recei...

journal_title：Journal of the American Academy of Dermatology

authors： Kossida T,Rigopoulos D,Katsambas A,Anderson RR

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:Intravenous immunoglobulin (IVIG) is used to treat many inflammatory and autoimmune disorders and although generally well tolerated, cutaneous side effects occur. OBJECTIVE:We reviewed reports of pompholyx and eczematous reactions associated with IVIG. METHODS:A literature search was performed using the ...

journal_title：Journal of the American Academy of Dermatology

authors： Gerstenblith MR,Antony AK,Junkins-Hopkins JM,Abuav R

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Adults are advised to wear sunscreen with a sun protection factor (SPF) of 15 or higher, apply it up to 30 minutes before sun exposure, and reapply it after 2 hours to reduce exposure to ultraviolet radiation in sunlight for the prevention of skin cancer. OBJECTIVE:This study investigated the extent to whic...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Andersen PA,Walkosz BJ,Scott MD,Maloy JA,Dignan MB,Cutter GR

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is a common skin cancer for which the treatment and recurrence risk correlate with the histologic subtype. Limited information is available regarding the accuracy of biopsy in diagnosing BCC subtypes. OBJECTIVE:We sought to determine the correlation between BCC subtypes present in...

journal_title：Journal of the American Academy of Dermatology

authors： Haws AL,Rojano R,Tahan SR,Phung TL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although twice-daily application of propylene glycol-containing 2% minoxidil topical solution (MTS) stimulates new hair growth, higher concentrations of minoxidil in a once-daily, propylene glycol-free formulation may improve efficacy and reduce unpleasant side effects. OBJECTIVE:We sought to compare the ef...

journal_title：Journal of the American Academy of Dermatology

authors： Blume-Peytavi U,Hillmann K,Dietz E,Canfield D,Garcia Bartels N

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Although several studies have documented an undersupply of dermatologic services in the United States, little is known about the dermatopathology workforce. OBJECTIVE:Objectives included the following: (1) describe the dermatopathology workforce in the United States; (2) identify characteristics associated ...

journal_title：Journal of the American Academy of Dermatology

authors： Suwattee P,Cham PM,Abdollahi M,Warshaw EM

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Dermatoscopy is the most commonly used noninvasive tool for the diagnosis of pigmented skin lesions, but few studies have investigated the value of cytology in the identification of those lesions. OBJECTIVE:We compared the accuracy of dermatoscopy with that of the Tzanck smear test in the diagnosis of pigme...

journal_title：Journal of the American Academy of Dermatology

authors： Durdu M,Baba M,Seçkin D

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Exposure to ultraviolet radiation (from solar and nonsolar sources) is a risk factor for skin cancer. OBJECTIVE:We sought to summarize recent estimates on sunburns, sun-protection behaviors, and indoor tanning available from national and selected statewide behavioral surveys. METHODS:Estimates of the preva...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Cokkinides V,Hall HI,Hartman AM,Saraiya M,Miller E,Paddock L,Glanz K

更新日期：2011-11-01 00:00:00

abstract：:There is significant confusion in the literature when describing vascular anomalies, and vascular malformations are often misnamed or incorrectly classified. Part I of this two-part series on the diagnosis and management of extensive vascular malformations of the lower limbs will discuss the dermatologist's role in th...

journal_title：Journal of the American Academy of Dermatology

authors： Redondo P,Aguado L,Martínez-Cuesta A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:An estimated 750,000 melanoma survivors in the United States are at increased risk of subsequent primary cancers. OBJECTIVE:We sought to assess the risk of developing subsequent primary cancers among people with cutaneous melanoma. METHODS:Using 1992 to 2006 data from the National Cancer Institute Surveill...

journal_title：Journal of the American Academy of Dermatology

authors： Balamurugan A,Rees JR,Kosary C,Rim SH,Li J,Stewart SL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulo...

journal_title：Journal of the American Academy of Dermatology

authors： von Bubnoff D,Scheler M,Wilms H,Wenzel J,von Bubnoff N,Häcker G,Schultze J,Popov A,Racz P,Bieber T,Wickenhauser C

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:UVA induces tissue damage via the production of radical oxygen species. Adding antioxidants to UV filters in sunscreens is a novel photoprotective strategy. The topical application of antioxidants in sunscreen can potentially neutralize the UVA-induced free radicals. OBJECTIVES:We sought to assess the degre...

journal_title：Journal of the American Academy of Dermatology

authors： Wang SQ,Osterwalder U,Jung K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The continuous increase in the US population older than 65 years and the chronic course of psoriasis make management of psoriasis in the elderly an important health care problem. OBJECTIVE:We sought to develop a treatment algorithm for patients with psoriasis who are older than 65 years. METHODS:A systemat...

journal_title：Journal of the American Academy of Dermatology

authors： Grozdev IS,Van Voorhees AS,Gottlieb AB,Hsu S,Lebwohl MG,Bebo BF Jr,Korman NJ,National Psoriasis Foundation.

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:To prevent DNA damage caused by the ultraviolet (UV) radiation of sunlight, sunscreens are commonly used to protect human skin. Current analysis of sunscreens' effectiveness is done through complicated procedures, including human exposure. OBJECTIVE:We sought to design a simple system using thymidine-thymid...

journal_title：Journal of the American Academy of Dermatology

authors： Maw KL,Caton-Williams J,Salon J,Huang Z

更新日期：2011-08-01 00:00:00

abstract：:Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification, metastatic calcification, idiopathic calcification, iatrogenic calcification, and calciphylaxis. Dystrophic calcification appears a...

journal_title：Journal of the American Academy of Dermatology

authors： Reiter N,El-Shabrawi L,Leinweber B,Berghold A,Aberer E

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Dermatomyositis (DM) is a multisystem autoimmune disease, in which serologic evidence of immune responses to disease-specific antigenic targets is found in approximately 50% to 70% of patients. Recently, melanoma differentiation-associated gene 5 (MDA5) has been identified as a DM-specific autoantigen that a...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino D,Chung L,Zwerner J,Rosen A,Casciola-Rosen L

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Primary closure of surgical defects after excision of cutaneous malignancies has been traditionally accomplished with layered closure. OBJECTIVE:We sought to compare the cosmetic outcome of cheek defects repaired with layered closure versus buried sutures and adhesive strips. METHODS:In all, 38 patients un...

journal_title：Journal of the American Academy of Dermatology

authors： Plotner AN,Mailler-Savage E,Adams B,Gloster HM Jr

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Serum levels of S100A8/A9 may correlate with disease activity in psoriasis. OBJECTIVE:We sought to elucidate the association of serum levels of S100A8/A9 heterodimers with the clinical subtypes of psoriasis and the major cell source. METHODS:Serum samples were collected from patients with psoriasis vulgari...

journal_title：Journal of the American Academy of Dermatology

authors： Aochi S,Tsuji K,Sakaguchi M,Huh N,Tsuda T,Yamanishi K,Komine M,Iwatsuki K

更新日期：2011-05-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:Digital squamous cell carcinoma (SCC) presents a diagnostic challenge because of its relatively rare occurrence and mimicry of benign conditions. Although low-risk human papillomavirus (HPV) subtypes are commonly associated with benign digital verrucae, digital SCC can be associated with high-risk, oncogenic HPV subty...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Groft CM,Miller CJ,Kovarik CL

更新日期：2011-05-01 00:00:00

abstract：:Phototherapy is a mainstay in the treatment of psoriasis and is available as psoralen plus UVA (PUVA), broadband UVB (BB-UVB), and narrowband UVB (NB-UVB). Phototherapy can be administered in the hospital, outpatient clinic, or in the patient's home. The purpose of this review is to provide some practical guidance to ...

journal_title：Journal of the American Academy of Dermatology

authors： Lapolla W,Yentzer BA,Bagel J,Halvorson CR,Feldman SR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Onychomatricoma (OM) is a rare benign tumor of the nail matrix in which genome-wide analyses have never been performed. It is clinically characterized by an increased transversal curvature of the nail plate, a longitudinal yellowish discoloration, and splinter hemorrhages. Once the nail plate has been remove...

journal_title：Journal of the American Academy of Dermatology

authors： Cañueto J,Santos-Briz Á,García JL,Robledo C,Unamuno P

更新日期：2011-03-01 00:00:00

abstract：:Superantigens (SAgs) are virulent polypeptides that are produced by a variety of infectious organisms. They are capable of causing nonspecific T cell activation by circumventing normal antigen processing in the human host. The genetic makeup of the host plays a role in conferring susceptibility or protection against S...

journal_title：Journal of the American Academy of Dermatology

authors： Macias ES,Pereira FA,Rietkerk W,Safai B

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Incontinentia pigmenti (IP) is a multisystem disorder, in which cutaneous symptoms can be accompanied by dental, ocular, and central nervous system defects. In adults, the clinical diagnosis of IP is based principally on the late onset of stage 4 lesions and their association with dental, nail, ocular, or ce...

journal_title：Journal of the American Academy of Dermatology

authors： Hadj-Rabia S,Rimella A,Smahi A,Fraitag S,Hamel-Teillac D,Bonnefont JP,de Prost Y,Bodemer C

更新日期：2011-03-01 00:00:00

abstract：:Many physicians in the United States and other nonendemic countries lack familiarity with New World cutaneous leishmaniasis (CL) and fail to include it in their differential diagnosis when seeing patients with suggestive lesions and recent high-risk travel. Moreover, even when the diagnosis of New World CL is consider...

journal_title：Journal of the American Academy of Dermatology

authors： Zaghi D,Panosian C,Gutierrez MA,Gregson A,Taylor E,Ochoa MT

更新日期：2011-03-01 00:00:00